E. NEOPLASIA

Introduction Moritz Kaposi initially described the clinical manifestations of classic Kaposi’s sarcoma (KS) as a disease with skin lesions and enlarged lymph nodes in 1872. He named it an “idiopathic multiple pigmented sarcoma”. However, the disease really came into the limelight in 1981 when 26 homosexual men in the United States were diagnosed with a […]

Introduction HIV-associated lymphomas are predominantly aggressive B-cell lymphomas. According to the World Health Organization (WHO) classification, HIV-associated systemic non-Hodgkin’s lymphomas (HIV-NHLs) include diffuse large B-cell lymphoma (DLBCL), HIV-associated primary central nervous system lymphoma (HIV-PCNSL), Burkitt lymphoma (BL), primary effusion lymphoma (PEL) and plasmablastic lymphoma of the oral cavity. Hodgkin disease, though not an AIDS-defining condition, […]

Introduction Worldwide, cancer is the third leading cause of death. Evolving demographic shift leads to the projection that cancer cases and deaths will double globally over the next 20-40 years. HIV infection poses an increased risk of cancers, the cause of which is multifactorial. HIV-associated immunosuppression compromises the ability to mount an immune response against […]