Introduction Although the very first antiretroviral regimen for a treatment-naive patient is designed for the long term, changes may be necessary with time as indicated by clinical needs or simply patient preference. With the current generation of drugs, virologic suppression is now almost taken for granted. This is followed by immunologic and clinical recovery. As […]

Introduction Twenty years into the highly active antiretroviral therapy (HAART) era, the pace of new drug development has not slowed. Compared to its first generation, HAART of today has become more tolerable, convenient, resilient and, at the same time, less toxic. The trend of increasing rates of viral suppression has become evident.[1] Lifelong successful therapy […]