Introduction Antiretroviral therapy plays a key role in the clinical management of people living with HIV/AIDS (PLWHA).[Chapter C10] Application of antiretroviral therapy, as evidenced in studies demonstrating impacts on virus transmission, is complementing behavioural intervention as a new approach to HIV prevention referred as biomedical HIV prevention. In practice, antiretrovirals (ARV) are an integral part […]
Kenny Chi-Wai CHAN
MBBS, FRCP(Edin), FHKAM(Medicine)
Dr Chan is a Specialist in Infectious Diseases and currently Consultant of Special Preventive Programme of the Centre for Health Protection, Hong Kong.
Introduction Twenty years into the highly active antiretroviral therapy (HAART) era, the pace of new drug development has not slowed. Compared to its first generation, HAART of today has become more tolerable, convenient, resilient and, at the same time, less toxic. The trend of increasing rates of viral suppression has become evident. Lifelong successful therapy […]
Introduction Although the very first antiretroviral regimen for a treatment-naive patient is designed for the long term, changes may be necessary with time as indicated by clinical needs or simply patient preference. With the current generation of drugs, virologic suppression is now almost taken for granted. This is followed by immunologic and clinical recovery. As […]
Introduction HIV is transmitted predominantly by sexual contact and needle-sharing in people who who inject drugs (PWID), and is thus closely associated with risk behaviours in the community. In some parts of the world, mother-to-child transmission (MTCT)[Chapter F33] is also important. Although the health care setting is not a natural venue for HIV transmission from […]